Medicine and Pharmacology2 Essay Example | Topics and Well Written Essays - 3000 words - 1

Medicine and Pharmacology2 - Essay Example here is also evidence showing that ATP is a cotransmitter with norepinephrine, where ATP may be a cotransmitter with acetylcholine (ACh) in certain postganglionic parasympathetic nerves (Brake and Julius, 1996). The purinergic receptors are found on the cell surface. These may be divided into the adenosine (P1) receptors and the receptors for ATP (P2X and P2Y receptors). P1 and P2 receptors have been known to have various subtypes. There are four adenosine receptors, namely A1, A2A, A2B, and A3 and multiple subtypes of P2X and P2Y receptors throughout the body. It has been suggested that these adenosine receptors and the P2Y receptors act via the G proteins to mediate physiological responses. On the other hand, the P2X receptors act through ion channels that are ligand gated (Burnstock, 2006). Following extensive research, it has now been established that ATP is a cotransmitter with classic transmitters both at in both the peripheral and central nervous systems, and through purinergic systems, purines are also powerful extracellular messengers to nonneuronal cells. The presence of purinergic signaling system in extraneural tissues such as exocrine, endocrine, secretory, endothelial, musculo skeletal, immune, and inflammatory cellular systems has been established (Burnstock and Knight, 2004). As this indicates, the distribution and functional roles of these P2 receptors have been elucidated further with ongoing research. In short, the purinergic signaling system is a rapid synaptic neurotransmitter system. This is involved in contraction and relaxation of smooth muscle and in exocrine and endocrine secretion. It has been evident now that purinergic signaling regulates many long-term cellular events in all tissues. These functions include cell proliferation, differentiation, migration, and death in cell development, cellular regeneration, and hence in wound healing. Another area is embryonic development where both P2X and P2Y receptors play prominent roles both

Arguments Assignment Example | Topics and Well Written Essays - 500 words

Arguments - Assignment Example Conclusion: Casey Anthony murdered her daughter. My argument is everyone deserves a fair trial. It would be better for murderers to go free than one innocent person is sentenced to death row or jail. My friend’s argument is murderers must be punished even if some innocent people are sent to jail or death row. I am just concerned if one person’s rights are violated, my rights could be violated. My friend takes the view it would never happen to her. We both walked away agreeing to disagree. 2. The Scope and Limits of Logic Logic can help individuals understand our arguments. By studying logic, individuals can understand how to look at both sides of an argument to make a decision. When an individual only looks at one side of the argument logic cannot take place. It is based on personal feelings and experiences instead of looking at different sides of the argument. No matter how obstinate or one sided a person can be, they still use logic in some circumstances. Everyday ind ividuals debate within themselves on actions. Whether it is to take the Interstate or a side road to work or school, people have to make decisions everyday. So everyone uses logic. By studying logic, an individual can understand the why and how they make decisions.